Effectiveness of DTaP Wanes Substantially Over Time

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MB: Here we have top vaccine zealots admitting that their religion isn’t true. The DTaP vaccine (diphtheria, tetanus, and acellular pertussis) does not prevent infection with the Bordetella pertussis bacterium. They seem surprised that vaccinated individuals show positive test results for infection with pertusis. They shouldn’t be — their surprise exhibits an ignorance about the basic effect of the acellular pertussis (aP) component of the vaccine. I have been researching this subject and have discovered that the pertussis vaccine (both acellular and whole cell versions) by definition is not bactericidal — it does not kill bacteria. Isn’t that a revelation? This vaccine is basically a cough suppressant, it is designed to reduce symptoms of pertussis infection (whooping cough). Vaccinated individuals can carry the pertussis bacteria and spread it to others. So when you hear public health morons blame outbreaks of pertussis on the unvaccinated, you know they are utterly misinformed about the function of the pertussis vaccine. They themselves could be spreading the germs to others (no matter how many times they have been vaccinated) because the vaccine is not bactericidal. But try explaining that fact to them and you will get this blank look of a zombie religious zealot with Stockholm Syndrome that cannot admit their religion isn’t true. Or you will get a violent attack saying you don’t know what you are talking about. By the way, the whole cell pertussis vaccine (which was finally eliminated from the US in 2002 after numerous neurological adverse events) has the same problem, it is not bactericidal. The problem is not with unvaccinated people, it is with an ineffective vaccine. One very interesting quote from this article is that the acellular pertusis vaccine is just as dangerous as the old whole cell vaccine. Other studies show the whole cell vaccine is no more bactericidal, contradicting this article which suggests we should return to that vaccine because it is more effective.

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Effectiveness of DTaP Wanes Substantially Over Time

‘The protective power of the diphtheria, tetanus, acellular pertussis vaccination (DTaP) wanes with time, according to a study presented here at the National Foundation for Infectious Diseases 14th Annual Conference on Vaccine Research.

“The most surprising finding is that the vaccine wanes as much as it does over time,” lead author Roger Baxter, MD, told Medscape Medical News. He is codirector of Kaiser Permanente’s Vaccine Study Center in Oakland, California, where he helps track and monitor the safety of vaccines for the US Centers for Disease Control and Prevention in Atlanta, Georgia.

Each year that elapses after vaccination is associated with a 36% increased risk of acquiring pertussis, he said.

“If you look over time, this means that whatever your DTaP vaccine was worth to begin with, at 3 years it’s 32% and at 5 years it’s 16% of your initial effectiveness,” Dr. Baxter told meeting attendees …

Dr. Levine later told Medscape Medical News that whole-cell vaccines, which are still used routinely in the developing world, were unfairly attacked in the past. “We’re seeing some of the downside of getting rid of the old whole-cell vaccine,” but it’s impossible to go back to whole cell, because of its detractors who impugned the vaccine for causing severe reactions, he said. “It really turns out that there’s no difference between acellular and the old whole cell for those rare severe events,” he said.’

Read the Article

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Characterization of Bactericidal Immune Responses following Vaccination with Acellular Pertussis Vaccines in Adults

‘Immunization did not result in improved bactericidal activity for any of the individuals, and in two cases immunization caused a statistically significant decrease in complement-mediated lysis …

In summary, booster immunization of adults with acellular pertussis vaccines was not found to increase bactericidal activity over preimmunization levels. Identifying ways to promote bactericidal immune responses might improve the efficacy of acellular pertussis vaccines.’

Read the Study

Pertussis Infection in Fully Vaccinated Children in Day-Care Centers, Israel

‘Vaccinated children may be asymptomatic reservoirs for infection …

We demonstrated B. pertussis infection in fully vaccinated children ages 2-3 years and 5-6 years who had contact with an infected child. We investigated whether younger or recently vaccinated children may be protected from classical clinical illness but remain susceptible to infection and become asymptomatic carriers.

All the children in the day-care centers had been immunized in infancy with all four doses of Pasteur diphtheria-tetanus toxoid pertussis (DTP) vaccine, which includes a booster dose at 12 months of age. The Pasteur vaccine contains 1 immunization dose (ID) of purified diphtheria toxoid, 1 ID of purified tetanus toxoid, and >4 IU of B. pertussis. All family members of the infant were also fully vaccinated with four doses of DTP. The infant had received only the first dose of vaccine at 2 months of age.

The whole-cell vaccine for pertussis is protective only against clinical disease, not against infection (15-17). Therefore, even young, recently vaccinated children may serve as reservoirs and potential transmitters of infection.’

Read the Study From the CDC Website

Acellular pertussis vaccines

‘The results were rather surprising. Despite epidemiological evidence from the USA showing evidence of high efficacy the American whole cell DTP vaccine gave only 36% protection (95% confidence interval (CI) 14 to 52%) in the Italian trial and 48% (95% CI 37 to 57%) in the Swedish trial.’

Read the Study

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One Response to Effectiveness of DTaP Wanes Substantially Over Time

  1. tal says:

    Always remember: efficacy is NOT effectiveness. In vaccination-speak efficacy (a surrogate marker) denotes the amount of circulating antibodies that can be measured in the vaccinee’s blood. Unfortunately, the amount of (artificially induced) circulating antibodies in a vaccinee’s blood does NOT correlate with immunity: some with a high rate prove to be susceptible; some with no detectable rate prove to be immune. The test is worthless but that’s the PharmaWay, is it not?

    Just like other vaccines, pertussis was declared to be effective so that an ‘immunized’ individual would always be diagnosed with something else. This strategy apparently worked until the mid-to-late 90s when it could no longer be ignored.

    The boy who introduced whooping cough into my daughter’s second grade class in the very early 90s had been diagnosed with parapertussis because he was fully vaccinated. It was only when a partially-vaccinated child caught the disease that it was ‘declared’ to be pertussis. Many people were eventually caught up in this outbreak and I spent years furious at the idiot doctor who had diagnosed the boy (whose single mom sent him back to school as soon as the fever had abated) before I understood that the Doc was simply following protocol.

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