Flu Vaccine Causes Inflammatory Response in Pregnant Women – Vaccine Journal

MB Comment: A new study shows an increase in inflammatory response among pregnant women who receive flu vaccine. This inflammatory response increases the risk of preeclampsia and preterm birth. Preeclampsia is a life-threatening condition characterized by a rapid rise in blood pressure that can lead to seizure, stroke, multiple organ failure and death of the mother and/or baby.

The CDC recommends flu vaccination for pregnant women. Most doctors will unquestioningly follow that CDC dictate. This new study is a stark warning to pregnant women about the safety of CDC-recommended vaccines. Health authorities apparently don’t mind killing you or your baby when they conduct a successful universal vaccination program. Their experts would claim it is a coincidence and state unequivocally that the benefits outweigh the risks.


Inflammatory responses to trivalent influenza virus vaccine among pregnant women.

Vaccine Journal  September 2011



In the U.S., seasonal trivalent influenza vaccination (TIV) is currently universally recommended for all pregnant women. However, data on the maternal inflammatory response to vaccination is lacking and would better delineate the safety and clinical utility of immunization. In addition, for research purposes, vaccination has been used as a mild immune trigger to examine in vivo inflammatory responses in nonpregnant adults. The utility of such a model in pregnancy is unknown. Given the clinical and empirical justifications, the current study examined the magnitude, time course, and variance in inflammatory responses following seasonal influenza virus vaccination among pregnant women.


Women were assessed prior to and at one day (n=15), two days (n=10), or approximately one week (n=21) following TIV. Serum interleukin (IL)-6, tumor necrosis factor (TNF)-α, C-reactive protein (CRP), and macrophage migration inhibitory factor (MIF) were determined by high sensitivity immunoassay.


Significant increases in CRP were seen at one and two days post-vaccination (ps<05). A similar effect was seen for TNF-α, for which an increase at two days post-vaccination approached statistical significance (p=.06). There was considerable variability in magnitude of response; coefficients of variation for change at two days post-vaccination ranged from 122% to 728%, with the greatest variability in IL-6 responses at this timepoint.


Trivalent influenza virus vaccination elicits a measurable inflammatory response among pregnant women. There is sufficient variability in response for testing associations with clinical outcomes. As adverse perinatal health outcomes including preeclampsia and preterm birth have an inflammatory component, a tendency toward greater inflammatory responding to immune triggers may predict risk of adverse outcomes, providing insight into biological mechanisms underlying risk. The inflammatory response elicited by vaccination is substantially milder and more transient than seen in infectious illness, arguing for the clinical value of vaccination. However, further research is needed to confirm that the mild inflammatory response elicited by vaccination is benign in pregnancy.

Read the Study

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2 Responses to Flu Vaccine Causes Inflammatory Response in Pregnant Women – Vaccine Journal

  1. mommagina says:

    Not to mention that the inserts on most injectable varieties of flu vaccine being used in the USA clearly state that there has been no testing to assess the effects on pregnant women. You can find insert information here: http://www.immunize.org/packageinserts/pi_influenza.asp Thanks for posting this article. I plan to share it with many pregnant women I know.

  2. Noreen says:

    Full Disclosure please. And these people call themselves Doctors? Mine recommended it and I questioned it. I have not felt the same since, my baby got Dx with Autism and I still have inflammatory problems, so does he. We need to have these company pay out! They are DOING the HARM and recommending things that are NOT healthy and are in fact putting our lives in jeopardy. Sux U Doc!

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